Makoto Hasegawa   Yasuhiro Osugi   Yoshifumi Moriwaki   Yohei Doi   
Fujita medical journal 10(1) 24-29 2024年2月
OBJECTIVES: Multidrug-resistant (MDR) bacterial infections are highly prevalent among long-term care facility (LTCF) residents, and are thus important targets for antimicrobial stewardship. Diagnoses of urinary tract infections (UTIs), which are a...
Aki Sakurai   Masahiro Suzuki   Kengo Hayashi   Yohei Doi   
Fujita medical journal 10(1) 8-15 2024年2月
OBJECTIVES: Taxonomic assignment based on whole-genome sequencing data facilitates clear demarcation of species within a complex genus. Here, we applied a unique pan-genome phylogenetic method, open reading frame (ORF)-based binarized structure ne...
William Bain   Brian Ahn   Hernán F Peñaloza   Christi L McElheny   Nathanial Tolman   Rick van der Geest   Shekina Gonzalez-Ferrer   Nathalie Chen   Xiaojing An   Ria Hosuru   Mohammadreza Tabary   Erin Papke   Naina Kohli   Nauman Farooq   William Bachman   Tolani F Olonisakin   Zeyu Xiong   Marissa P Griffith   Mara Sullivan   Jonathan Franks   Mustapha M Mustapha   Alina Iovleva   Tomeka Suber   Robert Q Shanks   Viviana P Ferreira   Donna B Stolz   Daria Van Tyne   Yohei Doi   Janet S Lee   
The Journal of infectious diseases 2024年1月
BACKGROUND: Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) bloodstream infections are associated with high mortality. We studied clinical bloodstream KPC-Kp isolates to investigate mechanisms of resistance to complement, a ke...
Richard D Smith   Min Zhan   Shanshan Zhang   Surbhi Leekha   Anthony Harris   Yohei Doi   Scott Evans   J Kristie Johnson   Robert K Ernst   
Journal of clinical microbiology 62(1) e0109623 2024年1月
Rapid diagnostic tests (RDTs) for bloodstream infections have the potential to reduce time to appropriate antimicrobial therapy and improve patient outcomes. Previously, an in-house, lipid-based, matrix-assisted laser desorption/ionization-time of...
Shu-Ting Cho   Emma G Mills   Marissa P Griffith   Hayley R Nordstrom   Christi L McElheny   Lee H Harrison   Yohei Doi   Daria Van Tyne   
bioRxiv : the preprint server for biology 2023年12月
Escherichia coli belonging to sequence type ST131 constitute a globally distributed pandemic lineage that causes multidrug-resistant extra-intestinal infections. ST131 E. coli frequently produce extended-spectrum β-lactamases (ESBLs), which confer...