Japanese | English

Researcher Database
Name: Hiroki Kurahashi
HomePage: http://www.fujita-hu.ac.jp/~genome/mg/
E-Mail address: kura@@fujita-hu.ac.jp

Organization / Department (#1)
Organization-1: Fujita Health University
Department(1) 1: Institute for Comprehensive Medical Science
Department(2) 1: Division of Molecular Genetics
Position-1: Professor
Address-1: 1-98,Toyoake Aichi JAPAN
Tel-1: +81-562-93-9391
FAX-1: +81-562-93-8831

Academic Meeting / Research Meeting (#1)
Academic Meeting-1: Japanese Society of Human Genetics
Academic Meeting / Research Meeting (#2)
Academic Meeting-2: Japanese Society for Genetic Counseling
Academic Meeting / Research Meeting (#3)
Academic Meeting-3: American Society of Human Genetics
Academic Meeting / Research Meeting (#4)
Academic Meeting-4: Japan Pediatric Society
Academic Meeting / Research Meeting (#5)
Academic Meeting-5: The Molecular Biology Society of Japan
Academic Meeting / Research Meeting (#6)
Academic Meeting-6: European Society of Human Genetics

Research History [2005] (#12)
Papers-12: 1. Inagaki, H., Ohye, T., Kogo, H., Yamada, K., Kowa, H., Shaikh, T.H., Emanuel, B.S., Kurahashi, H. (2005). A palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved among primates. Hum. Mutat., 26, 332-342.
2. Kurahashi, H., Taniguchi, M., Meno, C., Taniguchi, Y., Takeda, S., Horie, M., Otani, H., Toda, T. (2005). Basement membrane fragility underlies embryonic lethality in fukutin-null mice. Neurobiol. Dis., 19, 208-217.
3.Kano, H., Kurosawa, K., Horii, E., Ikegawa, S., Yoshikawa, H., Kurahashi, H. Toda, T. (2005). Genomic rearrangement at 10q24 in non-syndromic split-hand/split-foot malformation (SHFM). Hum. Genet., 118, 477-483.
4. Nagao, S., Kusaka, M., Nishii, K., Marunouchi, T., Kurahashi, H., Takahashi, H., Grantham, J. (2005). Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease. J. Am. Soc. Nephrol., 16, 2052-2062.
5. Kusaka, M., Yamada, K., Kuroyanagi, A., Terauchi, H., Kowa, H., Kurahashi, H., Hoshinaga, K. (2005). Gene expression profile in rat renal isografts from brain death donors. Transplant. Proc., 37, 364-366.
6. Toda, T., Chiyonobu, T., Xiong, H., Tachikawa, M., Kobayashi, K., Manya, H., Takeda, S., Taniguchi, M., Kurahashi, H., Endo, T. (2005) Fukutin and alpha-dystroglycanopahties. Acta Myologica, 24, 60-63.
Research History [2006] (#13)
Papers-13: 1. Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B.S., Kurahashi, H. (2006) Genetic variation affects de novo translocation frequency. Science, 311, 971.
2. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. (2006) Chromosomal translocations mediated by palindromic DNA. Cell Cycle, 5, 1297-1303.
3. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. (2006) Palindrome-mediated chromosomal translocations in humans. DNA Repair, 5, 1136-1145.
4. Ashley, T., Gaeth, A.P., Inagaki, H., Seftel, A., Cohen, M.M., Anderson, L., Kurahashi, H., Emanuel, B.S. (2006) Am. J. Hum. Genet., 79, 524-538.
5. Mori, T., Kurahashi, H., Shinka, T., Nakahori, Y., Taniguchi, M., Toda, T., Iwamoto, T. (2006) Candidate genes for male factor infertility-validation. Fertil. Steril., 86, 1553-1554.
6. Kinoshita, K., Shinka, T., Sato, Y., Kurahashi, H., Kowa, H., Chen, G., Umeno, M., Toida, K., Kiyokage, E., Nakano, T., Ito, S., Nakahori, Y. (2006) Molecular analysis of a mouse orthologue of HSFY, a candidate for the azoospermic factor on the human Y chromosome. J. Med. Invest., 53, 117-122.
7. Kawada, J., Kimura, H., Kamachi, Y., Nishikawa, K., Taniguchi, M., Nagaoka, K., Kurahashi, H., Kojima, S., Morishima, T. (2006) Analysis of gene expression profiles by oligonucleotide microarray in children with influenza. J. Gen. Virol., 87, 1677-1683.
8. Nagao, S., Nishii, K., Katsuyama, M., Kurahashi, H., Marunouchi, T., Takahashi, H., Wallace, D.P. (2006) Increased water intake decreases progression of polycystic kidney disease in the PCK rat. J. Am. Soc. Nephrol., 17, 2220-2227.
9. Taniguchi, M., Kurahashi, H., Noguchi, S., Fukudome, T., Okinaga, T., Tsukahara, T., Tajima, Y., Ozono, K., Nishino, I., Nonaka, I., Toda, T. (2006) Aberrant neuromuscular junctions and delayed terminal muscle fiber maturation in a-dystroglycanopathies. Hum. Mol. Genet., 15, 1279-1289.
10. Taniguchi, M., Kurahashi, H., Noguchi, .S, Sese, J., Okinaga, T., Tsukahara, T., Guicheney, P., Ozono, K., Nishino, I., Morishita, S., Toda, T. (2006) Expression profiling of muscles from Fukuyama-type congenital muscular dystrophy and laminin-α2 deficient muscular dystrophy; is congenital muscular dystrophy a primary fibrotic disease? Biochem. Biophys. Res. Commun., 342, 489-502.
11. Kusaka, M., Kuroyanagi, Y., Mori, T., Sasaki, H., Maruyama, T., Hayakawa, K., Shiroki, R., Kurahashi, H., Hoshinaga, K. (2006) Up-regulation of osteopontin, chemokines, adhesion molecule, and heat shock proteins in 1-hour biopsy from cardiac death donor kidneys. Transplant. Proc., 38, 3347-3350.
12. Kogo, H., Ito, S., Moritoki, Y., Kurahashi, H., Fujimoto, T. (2006) Differential expression of caveolin-3 in mouse smooth muscle cells in vivo. Cell Tissue Res., 324, 291-300.
Research History [2007] (#14)
Papers-14: 1. Kurahashi, H., Inagaki, H., Hosoba. E., Kato, T., Ohye, T., Kogo, H., Emanuel, B.S. (2007) Molecular clonong of a translocation hotspot in 22q11. Genome Res., 17, 461-469.
2. Kogo, H., Inagaki, H., Ohye, T., Kato, T., Emanuel, B.S., Kurahashi, H. (2007) Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats. Nucleic Acids Res., 35, 1198-1208.
3. Kato, T., Yamada, K., Inagaki, H., Kogo, H., Ohye, T., Emanuel, B.S., Kurahashi, H. (2007) Age has no effect on de novo constitutional t(11;22) translocation frequency in sperm. Fertil. Steril., 88, 1446-1448.
4. Tokuda, M., Kadokawa, Y., Kurahashi, H., Marunouchi, T. (2007) CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes. Biol. Reprod., 76, 130-141.
5. Kano, H., Kurahashi, H., Toda, T. (2007) Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype. Proc. Natl. Acad. Sci. U.S.A., 104, 19034-19039.
6. Nishizawa, H., Pryor-Koishi, K., Kato, T., Kowa, H., Kurahashi, H., Udagawa, Y. (2007) Microarray analysis of differentially expressed fetal genes in placental tissue derived from early and late onset severe pre-eclampsia. Placenta, 28, 487-497.
7. Nishizawa, H., Hasegawa, K., Suzuki, M., Achiwa, Y., Kato, T., Saito, K., Kurahashi, H., Udagawa, Y. (2007) The etiological role of allogeneic fetal rejection in pre-eclampsia. Am. J. Reprod. Immunol., 58, 11-20.
8. Kusaka, M., Kuroyanagi, Y., Kowa, H., Nagaoka, K., Mori, T., Yamada, K., Taniguchi, M., Shiroki, R., Kurahashi, H., Hoshinaga, K. (2007) Genome-wide expression profile in rat model of renal isografts from brain dead donors. Transplantation, 83, 62-70.
9. Pryor-Koishi, K., Nishizawa, H., Kato, T., Kogo, H., Murakami, T., Tsuchida, K., Kurahashi, H., Udagawa, Y. (2007) Overproduction of the follistatin-related gene protein in the placenta and maternal serum of women with pre-eclampsia. BJOG, 114, 1128-1137.
Research History [2008] (#15)
Papers-15: 1. Kato, T., Inagaki, H., Kogo, H., Ohye, T., Yamada, K., Emanuel, B.S., Kurahashi, H. (2008). Two different forms of palindrome resolution in the human genome: deletion or translocation. Hum. Mol. Genet., 17, 1184-1191.
2. Nishizawa, H., Pryor-Koishi, K., Suzuki, M., Kato, T., Kogo, H., Sekiya, T., Kurahashi, H., Udagawa, Y. (2008) . Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients. Mol. Hum. Reprod., 14, 595-602.
3. Nishizawa, H., Hasegawa, K., Suzuki, M., Achiwa, Y., Kato, T., Saito, K., Kurahashi, H., Udagawa, Y. (2008). Mouse model for allogeneic fetal rejection recapitulates human pre-eclampsia. J. Obstet. Gynaecol. Res., 34, 1-6.
4. Nagao, S., Nishii, K., Yoshihara, D., Kurahashi, H., Nagaoka, K., Yamashita, T., Takahashi, H., Yamaguchi, T., Calvet, J.P., Wallace, D.P. (2008). Calcium channel inhibition with verapamil accelerates polycystic kidney disease progression in the Cy/+ rat. Kidney Int., 73, 269-277.
5. Nakajima, Y., Tsuge, I., Kondo, Y., Komatsubara, R., Hirata, N., Kakami, M., Kato, M., Kurahashi, H., Urisu, A., Asano, Y. (2008). Up-regulated cytokine inducible SH2-containing protein expression in allergen-stimulated T cells from hen’s egg-allergic patients. Clin. Exp. Allergy, 38, 1499-1506.
6. Ichino, M., Mori, T., Kusaka, M., Kuroyanagi, Y., Ishikawa, K., Shiroki, R., Kowa, H., Kurahashi, H., Hoshinaga, K. (2008). Global gene expression profiling on renal scarring in rat model of pyelonephritis. Pediatr. Nephrol., 23, 1059-1071.
7. Kusaka, M., Kuroyanagi, Y., Mori, T., Nagaoka, K., Sasaki, H., Maruyama, T., Hayakawa, K., Shiroki, R., Kurahashi, H., Hoshinaga, K. (2008). Serum neutrophil gelatinase-associated lipocalin as a predictor of organ recovery from delayed graft function after kidney transplantation applying donation after cardiac death. Cell Transplant., 17, 129-134.
Research History [2009] (#16)
Papers-16: 1. Inagaki, H., Ohye, T., Kogo, H., Kato, T., Bolor, H., Taniguchi, M., Shaikh, T.H., Emanuel, B.S., Kurahashi, H. (2009). Chromosomal instability mediated by non-B DNA: Cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. Genome Res., 19, 191-198.
2. Bolor, H., Mori, T., Nishiyama, S., Ito, Y., Hosoba, E., Inagaki, H., Kogo, H., Ohye, T., Makiko, T., Kato, T., Tong, M., Nishizawa, H., Pryor-Koishi, K., Kitaoka, E., Sawada, T., Nishiyama, Y., Udagawa, Y., Kurahashi, H. (2009). Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am. J. Hum. Genet., 84, 14-20.
3. Kurahashi, H., Inagaki, H., Kato, T., Hosoba, E., Kogo, H., Ohye, T., Tsutsumi, M., Bolor, H., Tong, M., Emanuel, B.S. (2009). Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells. Hum. Mol. Genet., 18, 3397-3406.
4. Kurahashi, H., Bolor, H., Kato, T., Kogo, H., Tsutsumi, M., Inagaki, H., Ohye, T. (2009). Recent advance in our understanding of the molecular nature of chromosomal abnormalities. J. Hum. Genet., 54, 253-260.
5. Nishizawa, H., Pryor-Koishi, K., Suzuki, M., Kato, T., Sekiya, T., Tada, S., Kurahashi, H., Udagawa, Y. (2009). Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia. Gynecol. Obstet. Invest., 68, 239-247.
6. Ichino, M., Kuroyanagi, Y., Kusaka, M., Mori, T., Ishikawa, K., Shiroki, R., Kurahashi, H., Hoshinaga, K. (2009). Increased urinary neutrophil gelatinase-associated lipocalin levels in a rat model of upper urinary tract infection. J. Urol., 181, 2326-2331.
7. Kusaka, M., Kuroyanagi, Y., Mori, T., Nagaoka, K., Sasaki, H., Maruyama, T., Hayakawa, K., Shiroki, R., Kurahashi, H., Hoshinaga, K. (2009). Global expression profiles in one hour biopsy of human kidney transplantation from donors after cardiac death. Cell Transplant., 18, 647-656.

Fri Nov 19 15:42:55 JST 2010

Login page
All Page