Researcher Database
Name： Tamae Ohye

HomePage： http://www.fujita-hu.ac.jp/~genome/11&22

E-Mail address： otamae@fujita-hu.ac.jp

Organization / Department (#1)

Organization-1： Fujita Health University

Department(1) 1： Institute for Comprehensive Medical Science

Department(2) 1： Division of Molecular Genetics

Position-1： Research　Associate

Address-1： 1-98,Toyoake aichi JAPAN

Research History [2004] (#11)

Papers-11： 1.Kurahashi H, Inagaki H, Yamada K, Ohye T, Taniguchi M, Emanuel BS, Toda T. (2004) Cruciform DNA structure underlies the etiology for palindrome-mediated human chromosomal translocations. J Biol Chem., 279,35377-35383.

Speaker-11： 1. T. Ohye, H. Inagaki, H. Kogo, B.S. Emanuel, H. Kurahashi (2004) Development of yeast model system for palindrome-mediated chromosomal translocation. 54th American Society of Human Genetics, Toronto Canada, October, 26-30.

Research History [2005] (#12)

Papers-12： Inagaki, H., Ohye, T., Kogo, H., Yamada, K., Kowa, H., Shaikh, T.H., Emanuel, B.S., Kurahashi, H. (2005). A palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved among primates. Hum. Mutat., 26, 332-342.
Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B.S., Kurahashi, H. Genetic variation affects de novo translocation frequency. Science, in press.
Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. Palindrome-mediated chromosomal translocations in humans. DNA Repair, in press.

Speaker-12： Ohye, T., Inagaki, H., Kogo, H., Emanuel, B.S., Kurahashi, H. (2005). Yeast model system reveals the mechanism of palindrome-mediated chromosomal translocation. 55th annual meeting of American Society of Human Genetics, Salt Lake, USA, October, 25-29.
Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Emanuel, B.S., Kurahashi, H. (2005). Polymorphism of the palindromic sequence at the 11q23 breakpoint region affects de novo t(11;22) translocation frequency. 55th Annual Meeting of American Society of Human Genetics, Salt Lake City, USA, October, 25-29.

Research History [2006] (#13)

Papers-13： 1. Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B.S., Kurahashi, H. (2006) Genetic variation affects de novo translocation frequency. Science, 311, 971.
2. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. (2006) Chromosomal translocations mediated by palindromic DNA. Cell Cycle, 5, 1297-1303.
3. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. (2006) Palindrome-mediated chromosomal translocations in humans. DNA Repair, 5, 1136-1145.

Research History [2007] (#14)

Papers-14： 1. Kurahashi, H., Inagaki, H., Hosoba. E., Kato, T., Ohye, T., Kogo, H., Emanuel, B.S. (2007) Molecular clonong of a translocation hotspot in 22q11. Genome Res., 17, 461-469.
2. Kogo, H., Inagaki, H., Ohye, T., Kato, T., Emanuel, B.S., Kurahashi, H. (2007) Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats. Nucleic Acids Res., 35, 1198-1208.
3. Kato, T., Yamada, K., Inagaki, H., Kogo, H., Ohye, T., Emanuel, B.S., Kurahashi, H. (2007) Age has no effect on de novo constitutional t(11;22) translocation frequency in sperm. Fertil. Steril., 88, 1446-1448.

Research History [2008] (#15)

Papers-15： 1.Kato, T., Inagaki, H., Kogo, H., Ohye, T., Yamada, K., Emanuel, B.S., Kurahashi, H. (2008) Two different forms of palindrome resolution in the human genome: deletion or translocation. Hum. Mol. Genet., 17, 1184-1191.

Research History [2009] (#16)

Papers-16： 1. Inagaki, H., Ohye, T., Kogo, H., Kato, T., Bolor, H., Taniguchi, M., Shaikh, T.H., Emanuel, B.S., Kurahashi, H. (2009). Chromosomal instability mediated by non-B DNA: Cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. Genome Res., 19, 191-198.
2. Bolor, H., Mori, T., Nishiyama, S., Ito, Y., Hosoba, E., Inagaki, H., Kogo, H., Ohye, T., Makiko, T., Kato, T., Tong, M., Nishizawa, H., Pryor-Koishi, K., Kitaoka, E., Sawada, T., Nishiyama, Y., Udagawa, Y., Kurahashi, H. (2009). Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am. J. Hum. Genet., 84, 14-20.
3. Kurahashi, H., Inagaki, H., Kato, T., Hosoba, E., Kogo, H., Ohye, T., Tsutsumi, M., Bolor, H., Tong, M., Emanuel, B.S. (2009). Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells. Hum. Mol. Genet., 18, 3397-3406.
4. Kurahashi, H., Bolor, H., Kato, T., Kogo, H., Tsutsumi, M., Inagaki, H., Ohye, T. (2009). Recent advance in our understanding of the molecular nature of chromosomal abnormalities. J. Hum. Genet., 54, 253-260.

Fri Nov 19 17:16:48 JST 2010

Researcher Database
Name：	Tamae Ohye
HomePage：	http://www.fujita-hu.ac.jp/~genome/11&22
E-Mail address：	otamae@fujita-hu.ac.jp

Organization / Department (#1)
Organization-1：	Fujita Health University
Department(1) 1：	Institute for Comprehensive Medical Science
Department(2) 1：	Division of Molecular Genetics
Position-1：	Research　Associate
Address-1：	1-98,Toyoake aichi JAPAN

Research History [2004] (#11)
Papers-11：	1.Kurahashi H, Inagaki H, Yamada K, Ohye T, Taniguchi M, Emanuel BS, Toda T. (2004) Cruciform DNA structure underlies the etiology for palindrome-mediated human chromosomal translocations. J Biol Chem., 279,35377-35383.
Speaker-11：	1. T. Ohye, H. Inagaki, H. Kogo, B.S. Emanuel, H. Kurahashi (2004) Development of yeast model system for palindrome-mediated chromosomal translocation. 54th American Society of Human Genetics, Toronto Canada, October, 26-30.
Research History [2005] (#12)
Papers-12：	Inagaki, H., Ohye, T., Kogo, H., Yamada, K., Kowa, H., Shaikh, T.H., Emanuel, B.S., Kurahashi, H. (2005). A palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved among primates. Hum. Mutat., 26, 332-342. Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B.S., Kurahashi, H. Genetic variation affects de novo translocation frequency. Science, in press. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. Palindrome-mediated chromosomal translocations in humans. DNA Repair, in press.
Speaker-12：	Ohye, T., Inagaki, H., Kogo, H., Emanuel, B.S., Kurahashi, H. (2005). Yeast model system reveals the mechanism of palindrome-mediated chromosomal translocation. 55th annual meeting of American Society of Human Genetics, Salt Lake, USA, October, 25-29. Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Emanuel, B.S., Kurahashi, H. (2005). Polymorphism of the palindromic sequence at the 11q23 breakpoint region affects de novo t(11;22) translocation frequency. 55th Annual Meeting of American Society of Human Genetics, Salt Lake City, USA, October, 25-29.
Research History [2006] (#13)
Papers-13：	1. Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B.S., Kurahashi, H. (2006) Genetic variation affects de novo translocation frequency. Science, 311, 971. 2. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. (2006) Chromosomal translocations mediated by palindromic DNA. Cell Cycle, 5, 1297-1303. 3. Kurahashi, H., Inagaki, H., Kogo, H., Ohye, T., Kato, T., Emanuel, B.S. (2006) Palindrome-mediated chromosomal translocations in humans. DNA Repair, 5, 1136-1145.
Research History [2007] (#14)
Papers-14：	1. Kurahashi, H., Inagaki, H., Hosoba. E., Kato, T., Ohye, T., Kogo, H., Emanuel, B.S. (2007) Molecular clonong of a translocation hotspot in 22q11. Genome Res., 17, 461-469. 2. Kogo, H., Inagaki, H., Ohye, T., Kato, T., Emanuel, B.S., Kurahashi, H. (2007) Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats. Nucleic Acids Res., 35, 1198-1208. 3. Kato, T., Yamada, K., Inagaki, H., Kogo, H., Ohye, T., Emanuel, B.S., Kurahashi, H. (2007) Age has no effect on de novo constitutional t(11;22) translocation frequency in sperm. Fertil. Steril., 88, 1446-1448.
Research History [2008] (#15)
Papers-15：	1.Kato, T., Inagaki, H., Kogo, H., Ohye, T., Yamada, K., Emanuel, B.S., Kurahashi, H. (2008) Two different forms of palindrome resolution in the human genome: deletion or translocation. Hum. Mol. Genet., 17, 1184-1191.
Research History [2009] (#16)
Papers-16：	1. Inagaki, H., Ohye, T., Kogo, H., Kato, T., Bolor, H., Taniguchi, M., Shaikh, T.H., Emanuel, B.S., Kurahashi, H. (2009). Chromosomal instability mediated by non-B DNA: Cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. Genome Res., 19, 191-198. 2. Bolor, H., Mori, T., Nishiyama, S., Ito, Y., Hosoba, E., Inagaki, H., Kogo, H., Ohye, T., Makiko, T., Kato, T., Tong, M., Nishizawa, H., Pryor-Koishi, K., Kitaoka, E., Sawada, T., Nishiyama, Y., Udagawa, Y., Kurahashi, H. (2009). Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am. J. Hum. Genet., 84, 14-20. 3. Kurahashi, H., Inagaki, H., Kato, T., Hosoba, E., Kogo, H., Ohye, T., Tsutsumi, M., Bolor, H., Tong, M., Emanuel, B.S. (2009). Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells. Hum. Mol. Genet., 18, 3397-3406. 4. Kurahashi, H., Bolor, H., Kato, T., Kogo, H., Tsutsumi, M., Inagaki, H., Ohye, T. (2009). Recent advance in our understanding of the molecular nature of chromosomal abnormalities. J. Hum. Genet., 54, 253-260.