Rainbow trout and Atlantic salmon interleukin-4/13A (IL-4/13A) genes were identified. They were found expressed at high level in thymus, gill, and skin, in concert with the transcription factor gene GATA-3. High expression levels of IL-4, IL-13, a...
Ken Ohashi Fumio Takizawa Norihiro Tokumaru Chihaya Nakayasu Hideaki Toda Uwe Fischer Tadaaki Moritomo Keiichiro Hashimoto Teruyuki Nakanishi Johannes Martinus Dijkstra
IMMUNOGENETICS 62(8) 543-559 2010年8月 [査読有り]
In teleost fish, a novel gene G6F-like was identified, encoding a type I transmembrane molecule with four extracellular Ig-like domains and a cytoplasmic tail with putative tyrosine phosphorylation motifs including YxN and an immunoreceptor tyrosi...
Nobuhiro Hayashi Masami Takeuchi Teruyuki Nakanishi Keiichiro Hashimoto Johannes Martinus Dijkstra
FISH & SHELLFISH IMMUNOLOGY 28(1) 72-76 2010年1月 [査読有り]
The cytoplasmic tail of mammalian CD8 alpha binds the kinase LCK in a zinc-dependent manner. In analogy with a previous study for humans (Kim et al., 2003) peptides were synthesized from rainbow trout CD8a and LCK. Surface plasmon resonance (SPR) ...
Maki Ohtani Nobuhiro Hayashi Keiichiro Hashimoto Teruyuki Nakanishi Johannes Martinus Dijkstra
IMMUNOGENETICS 60(7) 383-397 2008年7月 [査読有り]
Interleukins 4 and 13 (IL-4 and IL-13) are related cytokines important for Th2 immune responses and encoded by adjacent genes on human chromosome 5. Efforts were made previously to detect these genes in fish, but research was hampered by a lack of...
Johannes Martinus Dijkstra Takayuki Katagiri Kazuyoshi Hosomichi Kazuyo Yanagiya Hidetoshi Inoko Mitsuru Ototake Takashi Aoki Keiichiro Hashimoto Takashi Shiina
Immunogenetics 59(4) 305-21 2007年4月 [査読有り]
Most of the previously studied teleost MHC class I molecules can be classified into two broad lineages: "U" and "Z/ZE." However, database reports on genes in cyprinid and salmonid fishes show that there is a third major lineage, which lacks detail...
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