H Yamaguchi   Y Kurosawa   K Hashimoto   
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 250(3) 558-564 1998年9月 [査読有り]
MR1 is a major histocompatibility complex (MHC) class I-related gene located outside the human MHC. Among several divergent class I molecules, the predicted MR1 molecule is closest, in the alpha 1 and alpha 2 domains, to the class I group to which...
We report the isolation and extensive analysis of highly polymorphic MHC class I genes from sharks (Triakis scyllia), which belong to the most primitive vertebrate group with jaws, the cartilaginous fish. Predicted complete peptide-binding domains...
H Yamaguchi   M Hirai   Y Kurosawa   K Hashimoto   
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 238(3) 697-702 1997年9月 [査読有り]
We report here a cDNA sequence of a murine homolog of the human major histocompatibility complex (MHC) class I-related gene, MR1. The analyses revealed unprecedentedly high conservation of MR1 in the alpha 1 and alpha 2 domains (corresponding to t...
K Hashimoto   M Hirai   Y Kurosawa   
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 230(1) 35-39 1997年1月 [査読有り]
Recently, a novel human major histocompatibility complex (MHC) class I-like gene (HLA-H) was reported as a candidate gene for human hereditary haemochromatosis, a recessive disease of iron metabolism with a remarkably high incidence in northern Eu...