Misa Suzuki-Anekoji   Atsushi Suzuki   Sz-Wei Wu   Kiyohiko Angata   Keith K Murai   Kazuhiro Sugihara   Tomoya O Akama   Kay-Hooi Khoo   Jun Nakayama   Michiko N Fukuda   Minoru Fukuda   
The Journal of biological chemistry 288(7) 5007-16 2013年2月
Chst10 adds sulfate to glucuronic acid to form a carbohydrate antigen, HNK-1, in glycoproteins and glycolipids. To determine the role of Chst10 in vivo, we generated systemic Chst10-deficient mutant mice. Although Chst10(-/-) mice were born and gr...
INTRODUCTION: Zinc coproporphyrin I (ZnCP-I) is a photosensitive molecule and a major component of meconium. Here, we examined the effects of ZnCP-I as a potential photosensitizer in photodynamic therapy for tumors. MATERIALS AND METHODS: (1) Aque...
Shingo Hatakeyama   Toshiaki K Shibata   Yuki Tobisawa   Chikara Ohyama   Kazuhiro Sugihara   Michiko N Fukuda   
Methods in molecular biology (Clifton, N.J.) 1022 369-86 2013年
Annexin A1 (Anxa1) is a highly specific surface marker of tumor vasculature. We used peptide-displaying phage technology to identify a carbohydrate ligand-mimicking 7-mer peptide, IFLLWQR (IF7), which can target Anxa1 in tumor vasculature. Here, w...
Seong Kyu Park   Jiwon Yoon   Ling Wang   Toshiaki K Shibata   Khatereh Motamedchaboki   Kyung Jun Shim   Mun Seog Chang   Seung Ho Lee   Naoaki Tamura   Shingo Hatakeyama   Daita Nadano   Kazuhiro Sugihara   Michiko N Fukuda   
Reproductive biology and endocrinology : RB&E 10(101) 101-101 2012年11月
BACKGROUND: Trophinin is an intrinsic membrane protein that forms a complex in the cytoplasm with bystin and tastin, linking it microtubule-associated motor dynein (ATPase) in some cell types. Previously, we found that human sperm tails contain tr...
Michiko N Fukuda   Kazuhiro Sugihara   
Sheng li xue bao : [Acta physiologica Sinica] 64(3) 247-58 2012年6月
The process of human embryo implantation is mediated not only by evolutionarily conserved mechanisms, but also by a mechanism unique to humans. Evidence suggests that the cell adhesion molecules, L-selectin and trophinin, play a unique role in hum...