The journal of obstetrics and gynaecology research 35(6) 1142-7 2009年12月
Cases of cancer presenting with microscopically confirmed metastatic malignancies for which no primary site can be detected are a challenge to stage clinically. Adenocarcinoma of unknown primary site is a subtype with high frequency that has no st...
BACKGROUND/PURPOSE: Photodynamic therapy (PDT) is a non-invasive cancer therapy that has a strong antitumor effect with intravenous administration of Photofrin. However, Photofrin causes light hypersensitivity that impairs the quality of life (QOL...
Aki Tanaka Yuko Suzuki Kazuhiro Sugihara Naohiro Kanayama Tetsumei Urano
Life sciences 85(5-6) 220-5 2009年7月
AIMS: Several activated coagulation factors have been reported to enhance fibrinolysis by inactivating plasminogen activator inhibitor type 1 (PAI-1), a serine protease inhibitor. We analyzed the interaction between PAI-1 and the three serine prot...
Chorangiosis is a vascular hyperplasia in the terminal chorionic villi, usually diagnosed histologically using the criteria of Altshuler. Its true etiology has not been fully identified, but chorangiosis has been proposed to result from a longstan...
Shingo Hatakeyama Kazuhiro Sugihara Jun Nakayama Tomoya O Akama Shuk-Man Annie Wong Hiroto Kawashima Jianing Zhang David F Smith Chikara Ohyama Minoru Fukuda Michiko N Fukuda
Proc. Natl. Acad. Sci. USA （PNAS） 106(9) 3095-100 2009年3月 [査読有り]
Cell surfaces of epithelial cancer are covered by complex carbohydrates, whose structures function in malignancy and metastasis. However, the mechanism underlying carbohydrate-dependent cancer metastasis has not been defined. Previously, we identi...
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医療科学部