At the Fujita Mind-Brain Research & Innovation Center for Drug Generation (Mind-BRIDGe), we are building a world-class research hub for eradicating mental and neurological disorders. By integrating “comprehensive knowledge” through collaboration with the humanities and social sciences, and using data science as our foundation, we promote the seamless integration of research and real-world implementation—encompassing genomes, molecules, cells, neural circuits, cognition and behavior, clinical practice, drug discovery, and mental health care. Our goal is to establish an unparalleled academic-driven drug discovery ecosystem.