2．Iida M, Tanaka M, Takagi T, Matsuki T, Kimura K, Shibata, K, Kobayashi Y, Mizutani Y, Kuwamura H, Yamada K, Kitaura H,
       Kakita A, Sakakibara M, Asai N, Takahashi M, and Asai M. Girdin deficiency causes developmental and
　   epileptic encephalopathy with hippocampal sclerosis and interneuronopathy Epilepsia. 66: 599-617. (2025)

3． Mihara K(10人省略、8番目). A novel method for generating chimeric antigenreceptor-transduced primary human natural
　　killer cells by the use of multiple cytokines and anti-CD2 and anti-NKp46 stimulatory antibodies. 　
　　Biomed Pharmacother. 2025 191:118505.

4． Mihara K(21人省略、13番目). Monoallelic mutations in MMD2 cause autosomal  dominant aggressive periodontitis.
　　J Exp Med. 2025 222(9):e20231911.

5． Mihara K(13人省略、12番目). Chimeric PD‑1 receptor redirects primary T cells  against childhood solid tumors but not to
　　PD‑1 ligand‑positive CD80‑coexpressing cells. Mol Med Rep. 2025 32(3):243.

6． Mihara K(5人省略、1番目). The Real World Impact of Immunoglobulin Replacement Therapy on Severe Bacterial
　　Infection for Patients With Hypogammaglobulinemia Secondary to Hematologic Malignancies: A Japanese
　　Claims Database Study. EJHaem. 2025 6(4):e70091. 

7． Mihara K(6人省略、5番目). Lipid-siRNA Conjugates Targeting High PD-L1 Expression as Potential Novel
　　Immune Checkpoint Inhibitors. Biomolecules. 2025 15(2):293.

1.  Watanabe K, Chiu H, Anderson DJ Whole-brain in situ mapping of neuronal activation in Drosophila during social
behaviors and optogenetic stimulation.eLife. 12: RP92380. (2024).

2．Kubo T, Yanagihara K, Nishimura Y, Iino Y, Komatsu T, Tansou R, Mihara K, Seyama T. Antitumor Effect of Oleoyl-siRNA against Pancreatic Cancer Using a Portal Vein Infusion Liver-Metastatic Mouse Model. 
Mol Pharm. 221: 5115-5125. (2024)

3．Kawamoto H, Kawase T, Nagano S. [Development of off-the-shelf universal T cell therapies from ES/iPS cells: applications in cancer and viral infection]. 
Rinsho Ketsueki. 65: 1075-1086. (2024)

4．Abe-Chayama H, Kawase T, Ichinohe T, Ishida Y, Tateno C, Hijikata M, Chayama K. Hepatitis B virus-specific human stem cell memory T cells differentiate into cytotoxic T cells and eradicate HBV-infected hepatocytes in mice. 
FEBS Lett. 598: 1354-1365. (2024)

5．Naoi H, Suzuki Y, Miyagi A, Horiguchi R, Aono Y, Inoue Y, Yasui H, Hozumi H, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Mii S, Ichihara M, Takahashi M, Suda, T. 
CD109 Attenuates Bleomycin-induced Pulmonary Fibrosis by Inhibiting TGF-b Signaling.  J Immunol. 212: 1221-1231. (2024)

6.  Ando R, Shiraki Y, Miyai Y, Shimizu H, Furuhashi K, Minatoguchi S, Kato K, Kato A, Iida T, Mizutani Y, Ito K, Asai N, Mii S, Esaki N, Takahashi M, Enomoto A.
Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas. J Pathol. 262: 61-75. (2024)

7．Owaki T, Iida T, Miyai Y, Kato K, Hase T, Ishii M, Ando R, Hinohara K, Akashi T, Mizutani Y, Ishikawa T, Mii S, Shiraki Y, Esaki N, Yamamoto M, Tsukamoto T, Nomura S, Murakami T, Takahashi M, Yuguchi Y et al. 
Synthetic retinoid-mediated preconditioning of cancer-associated fibroblasts and macrophages improves cancer response to immune checkpoint blockade.
Brit J Cancer. 131: 372-386. (2024)

１. Ando1 R, Shiraki Y, Miyai Y, Shimizu H, Furuhashi K, Minatoguchi S, Kato K, Kato A, Iida T, Mizutani Y, Ito K, Asai N, Mii S,
     EsakiiEsaki N, Takahashi M, Enomoto A.
     Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas.
     J Pathol. in press (2023)

２．Takahashi M. RET proto-oncogene.
      Molecular Diagnostics of Cancer (Intechopen) Editor: Dr. Pier Paolo Piccaluga

３．Mori N, Esaki N, Shimoyama Y, Shiraki Y, Asai N, Sakai T, Nishida Y, Takahashi M, Enomoto A, Mii S.
Significance of expression of CD109 in osteosarcoma and its involvement in tumor progression via BMP signaling.
Pathol Res Pract. 245:154443. (2023)

４．Aono Y, Suzuki Y, Horiguchi R, Inoue Y, Karayama M, Hozumi H, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Mii S, Takahashi M, Suda T.
CD109 on Dendritic Cells Regulates Airway Hyperreactivity and Eosinophilic Airway Inflammation. Am J Respir Cell Mol Biol. 68:201-212. (2023)

5．Sato T, Yamanaka Y, Ueno M, Sotozono C. Extra Eyelid-Derived Muscle Stem Cells. Methods Mol Biol. 2640:13-19. (2023)

6． Imai H, Kawase T, Yoshida S, Mese T, Roh S, Fujita A, Uchiki T, Sasaki A, Nagamatsu S, Takazawa A, Ichinohe T, Koshima I.
　　Peripheral T cell profilingreveals downregulated exhaustion marker and increased diversity in lymphedema post-lymphatic
　　venous anastomosis. iScience.2023;26(6):106822.

7.  Ito Y, Yamagata M, Yamamoto Y, Hirasaka K, Nikawa T, Sato T.
     The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle  atrophy.
     eLife, 12:RP89381.doi:10.7554/eLife.89381.(2023)

8．Iriyama C(15人省略, 1番目), Goto N(5番目), Mihara K(8番目), Miyama T(9番目), Tomita A(19番目). Utility of cerebrospinal fluid liquid biopsy in distinguishing CNS lymphoma from cerebrospinal infectious/demyelinating diseases. Cancer Med. 2023 12(16):16972-16984. 

5. Nakahara Y., Hashimoto N., Sakamoto K., Enomoto A., Adams T.S., Yokoi T., Omote N., Poli S., Ando A., Wakahara K., Suzuki A.,
    Inoue M., Hara A., Mizutani Y., Imaizumi K., Kawabe T., Rosas I.O., Takahashi M., Kaminski N. and Hasegawa Y.  　  Serum CD109 levels reflect the node metastasis status in head and neck squamous cell carcinoma. 　
       Cancer Med. 10: 1335-1346 (2021).

12. Kobayashi H., Gieniec K.A., Wright J.A., Wang T., Asai N., Mizutani Y., Ida T., Ando R., Suzuki N., Lannagan T.R.M., Ng J.Q.,
   　 Hara A., Shiraki Y., Mii S., Ichinose M., Vrbanac L., Lawrence M.J., Sammour T., Uehara 　 K., Davies G., Lisowski L.,
   　 Alexander I.E., Hayakawa Y., Butler L.M., Zannettino A.C.W., Din M.O., Hasty J., Burt A.D., Leedham S.J., Rustgi A.K.,
   　 Mukherjee S., Wang T.C., Enomoto A., Takahashi M., Worthley D.L. and Woods S.L. 　
  　  The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis.   　
   　 Gastroenterology 160: 1224-1239 (2021).

13．Mihara K(12人省略、10番目). Effectiveness of 4-1BB-costimulated HER2-targeted chimeric receptor T cell therapy for synovial sarcoma. Transl Oncol. 2021 14(12):101227.

1.  Esaki N, Enomoto A, Takagishi M, Mizutani Y, Iida T, Ushida K, Shiraki Y, Mii S. 
      and Takahashi M.The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt 
      signaling.Biochem Biophys Res Commun. 532:406-413 (2020).

2.  Chen C, Enomoto A, Weng L, Taki T, Shiraki Y, Mii S, Ichihara R, Kanda M, Koike M, 
　 Kodera Y. and Takahashi M.Complex roles of the actin-binding protein Girdin/GIV in DNA 
     damage-induced apoptosis of cancer cells.Cancer Sci. 111: 4303-4317 (2020).

3.  Taki T, Shiraki Y, Enomoto A, Weng L, Chen C, Asai N, Murakumo Y, Yokoi K, Takahashi M. 
      and Mii S.CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β 
　 signaling.Cancer Sci. 111: 4616-4628 (2020).
 
4.  Takagishi M, Esaki N, Takahashi K. and Takahashi M.Cytoplasmic Dynein Functions in 
　 Planar Polarization of Basal Bodies within Ciliated Cells.iScience 23:101213 (2020).
 
5.  Iida M, Tazaki A, Yajima I, Ohgami N, Taguchi N, Goto Y, Kumasaka Y.M, Prevost-BlondelA,
　 Kono M., Akiyama M., Takahashi M. and Kato M.Hair graying with aging in mice carrying 
　 oncogenic RET Aging Cell 19: e13273 (2020).
 
6.  Kawai K. and Takahashi M. Intracellular RET signaling pathways activated by GDNF. Cell Tissue Res. 382:113-123 (2020).
 
7.  Takahashi M., Kawai K. and Asai N.Roles of the RET Proto-oncogene in Cancer and Development JMA J. 3: 175-181 (2020).
 
8.  Kasahara Y, Shin C, Kubo N, Mihara K, Iwabuchi H, Takachi T, Imamura M, Saitoh A, Imai C.Development and
　 characterisation of NKp44-based  chimeric antigen receptors that confer T cells with NK cell-like specificity.
 　Clin Transl Immunology. 2020 Jul  8;9(7):e1147. doi: 10.1002/cti2.1147. PMID: 32670576; PMCID: PMC7341825. 
 
9.　Matsumura N, Sasaki N, Cho Y, Daimaru Y, Nojima T, Mizuno N, Takei Y, Mihara K. Rare 
　　primary extramedullary hematopoiesis of the thyroid without
　　intranodular vascularity and mutations in the JAK2, MPL, and calreticulin genes. Ann
　　Hematol. 2020 Sep;99(9):2211-2213. doi: 10.1007/s00277-020-04086-3. Epub 2020 May 21. PMID: 32440789.
 
10. Mizuno N, Kume K, Nagatani Y, Matsuda S, Iwata T, Ouhara K, Kajiya M, Takeda K, Matsuda
　　Y, Tada Y, Ohsawa R, Morino H, Mihara K, Fujita T,Kawaguchi H, Shiba H, Kawakami H, Kurihara H.
　　Aggressive periodontitis and NOD2 variants. J Hum Genet. 2020 Oct;65(10):841-846.
　   doi: 10.1038/s10038-020-0777-z. Epub 2020 May 19. PMID: 32424308. 

11. Mizuno N, Iwata T, Ohsawa R, Ouhara K, Matsuda S, Kajiya M, Matsuda Y, Kume K, Tada Y, 
　   Morino H, Yoshimoto T, Ueki Y, Mihara K, Sotomaru Y, Takeda K, Munenaga S, Fujita T, 
　   Kawaguchi H, Shiba H, Kawakami H, Kurihara 　H. Optineurin regulates osteoblastogenesis
　   through STAT1. Biochem Biophys Res Commun. 2020 May 14;525(4):889-894. doi: 10.
　   1016/j.bbrc.2020.03.028. Epub 2020 Mar 12. PMID:32171527